Research direction-1: Drugging the undruggable tumor suppressor

Background: In clinical oncology, there are about 80 approved small-molecule targeted drugs. Most of them target oncopro...

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Research direction-2: drugging ‘smooth’ proteins without druggable pockets

Background: Among the 568 established therapeutical anticancer targets (Martinez-Jimenez, Nat Rev Can, 2020, 20, 555-572...

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